|
ECOG E2805 |
A Randomized, Double-Blind Phase III Trial of Adjuvant Sunitinib vs. Sorafenib vs. Placebo in Patients with Resected Renal Cell Carcinoma |
Kidney |
Therapeutic |
Holcombe |
III |
Open |
|
ECOG PACCT-1 |
Phase III Randomized Study of Adjuvant Combination Chemotherapy and Hormonal Therapy versus Adjuvant Hormonal Therapy Alone in Women with Previously Resected Axillary Node-Negative Breast Cancer with Various Levels of Risk for Recurrence (TAILORx Trial) |
Breast - Female |
Therapeutic |
Mehta |
III |
Open |
|
GOG 0087M |
A Phase II Evaluation of Trabectedin (Yondelis, R279741, IND #75111) in the Treatment of Advanced, Persistent, or Recurrent Uterine Leiomyosarcomas |
Corpus Uteri |
Therapeutic |
Monk |
II |
Open |
|
GOG 0205 |
A Phase II Trial of Radiation Therapy and Weekly Cisplatin Chemotherapy for the Treatment of Locally-Advanced Squamous Cell Carcinoma of the Vulva |
Other Female Genital |
Therapeutic |
Burger |
II |
Open |
|
GOG 0209 |
Randomized Phase III Trial of Doxorubicin/Cisplatin/Paclitaxel and G-CSF versus Carboplatin/Paclitaxel in Patients With Stage III and Stage IV or Recurrent Endometrial Cancer |
Corpus Uteri |
Therapeutic |
Burger |
III |
Open |
|
GOG 0210 |
A Molecular Staging Study of Endometrial Carcinoma |
Corpus Uteri |
Correlative |
Burger |
N/A |
Open |
|
GOG 0212 |
A Randomized Phase III Trial of Maintenance Chemotherapy Comparing 12 Monthly Cycles of Single Agent Paclitaxel or Xyotax (CT-2103) (IND #70177) versus No Treatment Until Documented Relapse in Women with Advanced Ovarian or Primary Peritoneal Cancer Who Achieve a Complete Clinical Response to Primary Platinum/Taxane Chemotherapy |
Ovary |
Therapeutic |
Burger |
III |
Open |
|
GOG 0213 |
A Phase III Randomized Controlled Clinical Trial of Carboplatin and Paclitaxel Alone or in Combination with Bevacizumab Followed by Bevacizumab and Secondary Cytoreductive Surgery in Platinum-Sensitive, Recurrent Ovarian, Peritoneal Primary and Fallopian Tube Cancer. NCI-Supplied Agents: Bevacizumab NSC #704865 |
Ovary |
Therapeutic |
Burger |
III |
Open |
|
GOG 0218 |
A Phase III Trial of Carboplatin and Paclitaxel Plus Placebo versus Carboplatin and Paclitaxel Plus Concurrent Bevacizumab (Rhumab VEGF, NSC #704865, IND #7921) Followed by Placebo, versus Carboplatin and Paclitaxel Plus Concurrent and Extended Bevacizumab, in Women with Newly Diagnosed, Previously Untreated, Stage III or IV Epithelial Ovarian and Peritoneal Primary Cancer |
Ovary |
Therapeutic |
Burger |
III |
Open |
|
GOG 0219 |
A Phase III, Randomized Trial of Weekly Cisplatin and Radiation versus Cisplatin and Tirapazamine and Radiation in Stage IB2, IIA, IIB, IIIB and IVA Cervical Carcinoma Limited to the Pelvis |
Cervix |
Therapeutic |
Burger |
III |
Open |
|
GOG 136 |
Acquisition of Gynecologic Specimens and Serum to be Used in Studying the Causes, Diagnosis, Prevention, and Treatment of Cancer |
Ovary |
Repository/Registry |
Burger |
N/A |
Open |
|
GOG 9916 |
A Phase I Trial of Intravenous Paclitaxel Intraperitoneal Carboplatin and Intraperitoneal Paclitaxel or Intravenous Docetaxel, Intaperitoneal Carboplatin and Intraperitoneal Paclitaxel in Patients with Previously Untreated Epithelial Ovarian Carcinoma, Fallopian Tube or Primary Peritoneal Carcinoma |
Ovary |
Therapeutic |
Burger |
I |
Open |
|
GOG 9917 |
A Dose-Escalating Phase I Study with an Expanded Cohort to Assess the Feasibility of Intraperitoneal Carboplatin (NSC #214240) and Intravenous Paclitaxel (NSC #673089) in Patients with Previously Untreated Epithelial Ovarian, Primary Peritoneal or Fallopian Tube Carcinoma |
Ovary |
Therapeutic |
Burger |
I |
Open |
|
GOG 9919 |
A Phase I Trial of Dose Dense (Biweekly) Carboplatin Combined with Paclitaxel and Pegfilgrastim (NEULASTA): A Feasibility Study in Patients with Untreated Stage III and IV Ovarian, Tubal or Primary Peritoneal Cancer |
Ovary |
Therapeutic |
Burger |
I |
Open |
|
NSABP B-42 |
A Clinical Trial to Determine the Efficacy of Five Years of Letrozole Compared to Placebo in Patients Completing Five Years of Hormonal Therapy Consisting of an Aromatase Inhibitor (AI) or Tamoxifen Followed by an AI in Prolonging Disease-Free Survival in Postmenopausal Women
with Hormone Receptor Positive Breast Cancer |
Breast - Female |
Therapeutic |
Mehta |
III |
Open |
|
SWOG S0226 |
Phase III Randomized Trial of Anastrozole versus Anastrozole and Fulvestrant as First-Line Therapy for Post-Menopausal Women with Metastatic Breast Cancer |
Breast - Female |
Therapeutic |
Mehta |
III |
Open |
|
SWOG S0332 |
Phase III Randomized Trial of Preoperative Chemotherapy versus Preoperative Concurrent Chemotherapy and Thoracic Radiotherapy Followed by Surgical Resection and Consolidation Chemotherapy in Favorable Prognosis Patients with Stage IIIA (N2) Non-Small Cell Lung Cancer |
Lung |
Therapeutic |
Ou |
III |
Open |
|
SWOG S0424 |
Molecular Epidemiology Case-Series Study of Non-Small Cell Lung Cancer in Smoking and Non-Smoking Women and Men |
Lung |
EPI/Obs |
Ou |
N/A |
Open |
|
SWOG S9925 |
Lung Cancer Specimen Repository Protocol |
Lung |
Repository/Registry |
Holcombe |
N/A |
Open |
|
UCI 00-09 |
Angiogenesis in Early Breast Cancer for Prognosis Prediction |
Breast - Female |
Screening/Diagnostic/ED |
Su |
N/A |
Open |
|
UCI 00-55 |
Angiogenic Biomarkers Outcomes of Prostate Cancer at UCIMC |
Prostate |
Screening/Diagnostic/ED |
Ahlering |
N/A |
N/A |
|
UCI 01-14 |
Breast Cancer Family Registration of Special Populations |
Breast - Female |
Repository/Registry |
Anton-Culver |
|
N/A |
|
UCI 01-59 |
Development of a Diagnostic Assay for Kinase Activity in Malignant Cells |
Other Hematopoietic |
Screening/Diagnostic/ED |
Holcombe |
N/A |
Open |
|
UCI 02-10 |
Monitoring the Response of Chemotherapy on Breast Cancer Tumors by Photon Migration Spectroscopy |
Breast - Female |
Therapeutic |
Hsiang |
N/A |
Open |
|
UCI 02-22 |
Studies of Monocyte-Derived Dendritic Cell Biology: Application to Anti-tumor Immunotherapy |
Multiple |
Correlative |
Nelson |
N/A |
Open |
|
UCI 02-23 |
Phase II Evaluation of Docetaxel and Vinorelbine Plus Sargramostim in Patients with Metastatic Malignant Melanoma |
Melanoma, Skin |
Therapeutic |
Fruehauf |
II |
Open |
|
UCI 02-68 |
(1) SXR: A Target for Breast Cancer Prevention and Treatment
(2) Species Specific Xenobiotic Metabolism Mediated by the Steroid and Xenobiotic Receptor |
Breast - Female |
Correlative |
Blumberg |
N/A |
N/A |
|
UCI 02-69 |
A Phase I Clinical Trial of GM-CSF Administration as a Biological Adjuvant in Clinically-Staged, Resectable Pancreatic Adenocarcinoma |
Pancreas |
Therapeutic |
Nelson |
I |
Open |
|
UCI 03-03 |
Immunologic Factors Affecting Outcomes in Hepatocellular Carcinoma |
Liver |
Correlative |
Imagawa |
N/A |
Open |
|
UCI 03-11 |
A Randomized Phase II/III Study of TNFerade Biologic with 5-FU Radiation Therapy for First-Line Treatment of Unresectable Locally Advanced Pancreatic Cancer |
Pancreas |
Therapeutic |
Chang |
II/III |
Open |
|
UCI 03-16 |
A Phase II Chemoprevention Trial of Anastrozole in the DCIS and Early Invasive Breast Cancer in Postmenopausal Women |
Breast - Female |
Therapeutic |
Mehta |
II |
Open |
|
UCI 04-04 |
A Phase I Study of CCI-779 in Combination with Imatinib Mesylate in Chronic Myelogenous Leukemia |
Myeloid and Monocytic Leukemia |
Therapeutic |
Holcombe |
I |
Open |
|
UCI 04-05 |
Investigation into the Molecular Causes of Colon and Rectal Cancers |
Colon |
Correlative |
Holcombe |
N/A |
Open |
|
UCI 04-35 |
Evaluation of Oxaliplatin and Gemcitabine in Patients with Metastatic Bladder Cancer |
Kidney |
Therapeutic |
Fruehauf |
I |
Open |
|
UCI 04-60 |
Randomized Phase III Study of Docetaxel or Pemetrexed with or without Cetuximab in Patients with Recurrent or Progressive Non-Small Cell Lung Cancer after Platinum-Based Therapy |
Lung |
Therapeutic |
Ou |
III |
Open |
|
UCI 04-87 |
Measurement of Optical Properties of Adult Human Muscle Tissue |
Other |
Screening/Diagnostic/ED |
Cerrussi |
Pilot |
Open |
|
UCI 05-11 |
Retrospective Chart Review of Melanoma Patients Treated by Dr. Fruehauf |
Melanoma, Skin |
EPI/Obs |
Fruehauf |
N/A |
N/A |
|
UCI 05-16 |
Molecular Epidemiology of Non-Small-Cell Lung Carcinoma: The Role of Somatic Mutations in EGFR-1, ERBB2, K-ras, and BRAF |
Lung |
EPI/Obs |
Zell |
N/A |
N/A |
|
UCI 05-17 |
Psychosocial Telephone Counseling and Ovarian Cancer |
Ovary |
Supportive Care |
Wenzel |
N/A |
Open |
|
UCI 05-20 |
Resveratrol for Patients with Colon Cancer |
Colon |
Therapeutic |
Holcombe |
Pilot |
Open |
|
UCI 05-25 |
Timing of Rectal Cancer Response to Chemoradiation |
Rectum |
EPI/Obs |
Stamos |
N/A |
Open |
|
UCI 05-39 |
Molecular Epidemiology of Nasopharyngeal Carcinoma: The Role of Somatic Mutations in EGFR-1, ERBB2, K-ras, and BRAF |
Lip, Oral Cavity and Pharynx |
Repository/Registry |
Ou |
N/A |
N/A |
|
UCI 05-40 |
Stress, Immunity, and Cervical Cancer: Biobehavioral Outcomes of a Randomized Trial |
Cervix |
Supportive Care |
Wenzel |
N/A |
Open |
|
UCI 05-48 |
Retrospective Chart Review of Laparoscopic Radical Cystectomy |
Kidney |
EPI/Obs |
Ornstein |
N/A |
N/A |
|
UCI 05-49 |
Phase IIa Trial of Curcumin Among Patients with Prevalent Subclinical Neoplastic Lesions (Aberrant Crypt Foci) |
Colon |
Prevention |
Meyskens |
II |
Open |
|
UCI 05-50 |
The Radiosensitizing Effects of Oxaliplatin versus Cisplatin in Various Chemotherapy-regimen Combinations in Advanced Cervical Carcinoma Utilizing the In Vitro Chemo-Radiation Response Assay |
Cervix |
Correlative |
Randall |
N/A |
Open |
|
UCI 05-52 |
Molecular Epidemiology of Squamous Cell Carcinoma of the Head and Neck (SCCHN): The Role of Somatic Mutations in EGFR-1, ERBB2, K-ras, and BRAF and Genetic Polymorphism of the EGFR-1 |
Lip, Oral Cavity and Pharynx |
Repository/Registry |
Ou |
N/A |
N/A |
|
UCI 05-56 |
Role of Comprehensive Surgical Staging and Adjuvant Chemotherapy in Management of Noninvasive Papillary Serous Carcinoma of the Endometrium |
Corpus Uteri |
EPI/Obs |
Berman |
N/A |
N/A |
|
UCI 05-57 |
An Immunohistochemical Study of Uterine Papillary Serous Carcinoma (UPSC) and Its Clinicopathologic Significance |
Corpus Uteri |
EPI/Obs |
Berman |
N/A |
N/A |
|
UCI 05-62 |
The role of the ATM Gene in Familial Breast Cancer |
Breast - Female |
EPI/Obs |
Neuhausen |
|
N/A |
|
UCI 06-06 |
Randomized Double Blind, Placebo-Controlled Phase II Clinical Trial of Lovastatin for Various Endpoints of Melanoma Pathobiology |
Melanoma, Skin |
Prevention |
Linden |
II |
Open |
|
UCI 06-07 |
A Phase II, Randomized, Controlled Trial of the Safety and Efficacy of S-Adenosyl-L-Methionine Desulfate P-Toluene-Sulfonate (SAMe) in Reducing Serum Alpha Fetopreotein (AFP) in Patient with Hepatitis C and Moderately Elevated AFP |
Liver |
Prevention |
Hoefs |
II |
Open |
|
UCI 06-08 |
Evaluation of Disulfiram Plus Arsenic Trioxide in Patients with Metastatic Melanoma and at Least One Prior Systemic Therapy |
Melanoma, Skin |
Therapeutic |
Fruehauf |
I/II |
Open |
|
UCI 06-16 |
Optical Coherence Tomography for Early Detection and Staging of Endobronchial Lung and Pleural Cancer |
Lung |
Screening/Diagnostic/ED |
Brenner |
N/A |
Open |
|
UCI 06-22 |
A Multicenter, Randomized, Double-Blind, Placebo Controlled, Parallel-Arm Study of the Effect of Intravenous AVE005 (VEGF Trap) Administered Every 2 Weeks in Advanced Ovarian Cancer Patients with Recurrent Symptomatic Malignant Ascites |
Ovary |
Therapeutic |
Monk |
II |
Open |
|
UCI 06-23 |
A Phase II Double-Blind Dose Escalation Study of KRN5500 for Neuropathic Pain in Patients with Cancer (Protocol no. DTCL100) |
Multiple |
Therapeutic |
Sender |
II |
Open |
|
UCI 06-30 |
Phase IIa Trial Testing Erlotinib as an Intervention Against Intraductal Pancreatic Mucinous Neoplasms |
Pancreas |
Prevention |
Lipkin |
II |
Open |
|
UCI 06-32 |
A Pivotal Phase II Study of the Anti-Angiogenesis Agent AG-013736 in Patients with Metastatic or Unresectable Locally-Advanced Non-Anaplastic Thyroid Cancer Who are Refractory to or not Suitable Candidates for Anthracycline Treatment |
Thyroid |
Therapeutic |
Ou |
II |
Open |
|
UCI 06-47 |
Breast Cancer Stem/Progenitor Cell Repository Protocol |
Breast - Female |
Repository/Registry |
Butler |
N/A |
Open |
|
UCI 06-60 |
BMS CA180-0097: A Phase II Trial of Dasatinib (Sprycel®) in Subjects with Hormone-Refractory Prostate Cancer, Previously Treated with Chemotherapy |
Prostate |
Therapeutic |
Lilly |
II |
Open |
|
UCI 06-62 |
A Phase II Single-Arm Trial of BIBW 2992 in Non-Small Cell Lung Cancer Patients with EGFR Activating Mutations |
Lung |
Therapeutic |
Ou |
II |
Open |
|
UCI 07-02 |
A Multicenter, Randomized Double-Blind Placebo Controlled Phase III Study of the Efficacy of Xaliproden in Preventing the Neurotoxicity of Oxaliplatin in First-Line Treatment of Patients with Metastatic Colorectal Cancer Treated with Oxaliplatin/5-FU/LV |
Colon |
Therapeutic |
Holcombe |
III |
Open |
|
UCI 07-03 |
Determining the Utility of an Assessment Tool for Older Patients with Cancer |
Multiple |
Screening/Diagnostic/ED |
Sanati |
N/A |
Open |
|
UCI 07-16 |
Markers of Angiogenesis in Advanced Cervical Cancer |
Cervix |
Correlative |
Monk |
N/A |
N/A |
|
UCI 07-21 |
Retrospective Chart Review of Chemotherapy Outcomes |
Breast - Female |
EPI/Obs |
Mehta |
N/A |
N/A |
|
UCI 07-23 |
Improving Quality of Care for Breast Cancer Survivors |
Breast - Female |
EPI/Obs |
Lane |
N/A |
Open |
|
UCI 07-26 |
A Randomized, Double-Blind Placebo Controlled, Phase II Trial of Paclitaxel in Combination with AMG 386 in Subjects with Advanced Recurrent Ovarian Cancer |
Ovary |
Therapeutic |
Tewari |
II |
Open |
|
UCI 07-30 |
Vesicare (Solifenacin) in the Treatment of Urinary Incontinence after Radical Prostatectomy |
Urinary Bladder |
Supportive Care |
Ahlering |
N/A |
Open |
|
UCI 07-36 |
A Prospective, Multi-Center, Longitudinal Cohort Study of CryoSpray Ablation of Low Grade or High Grade Dysplasia within Barrett's Esophagus (LCS Dysplasia) |
Esophagus |
Therapeutic |
Muthusamy |
N/A |
Open |
|
UCI 07-40 |
Phase I Safety, Pharmacokinetic and Pharmacodynamic Study of PF-02341066, a C-MET/HGFR Selective Tyrosine Kinase Inhibitor, Administered Orally to Patients with Advanced Cancer |
Multiple |
Therapeutic |
Ou |
I |
Open |
|
UCI 07-50 |
A Randomized Phase III Study of Pemetrexed in Combination with Cisplatin versus Cisplatin Monotherapy in Patients with Recurrent or Metastatic Head and Neck Cancer |
Other |
Therapeutic |
Ou |
III |
Open |
|
UCI 07-55 |
A Randomized Trial of Temsirolimus and Sorafenib as Second-Line Therapy in Patients with Advanced Renal Cell Carcinoma, Who Have Failed First-Line Sunitinib Therapy |
Kidney |
Therapeutic |
Fruehauf |
III |
Open |
|
UCI 07-58 |
Phase I Biomarker Study of Dietary Grape-Derived Low Dose Resveratrol for Colon Cancer Prevention |
Colon |
Prevention |
Holcombe |
I |
Open |
|
UCI 07-61 |
A Phase II Study of Breast Cancer Treatment Using Weekly Carboplatin + Nab-paclitaxel, Plus Trastuzumab (HER2+) or Bevacizumab (HER2-) in the Neoadjuvant Setting |
Breast - Female |
Therapeutic |
Mehta |
II |
Open |
|
UCI 07-66 |
A Pilot Study to Evaluate the Correlation of Modified Two Layer Diffuse Optical Spectroscopy and SIAscopy as Compared to Clinical Examination and Histology of Pigmented Skin Lesions Based on Physiological Parameters |
Other Skin |
Screening/Diagnostic/ED |
Hsiang |
Pilot |
Open |
|
UCI 08-17 |
Expression of Wnt Signaling Inhibitors in Sarcomas |
Bones and Joints |
Correlative |
Hoang |
N/A |
N/A |
|
UCI 08-30 |
Predictors of follow-up after colposcopy: identifying women who are at high risk for progression of CIN |
Colon |
EPI/Obs |
Chase |
|
N/A |
|
UCI 08-32 |
Defining and Improving Access to Care for Spanish Speaking Patients with Brain Tumors |
Brain & Nervous System |
Supportive Care |
Bota |
|
Open |
|
UCI 08-33 |
Effects on colorectal cancer-CRC Survival and CRC risks by genes involved in arginine and polyamine metabolism and dietary factors |
Colon |
EPI/Obs |
Zell |
|
N/A |
|
UCI 08-35 |
A Prospective Study of GI trainees’ Proficiency in Attaining Quality Benchmarks in the Performance of Colonoscopy |
Colon |
Screening/Diagnostic/ED |
Muthusamy |
|
N/A |
|
UCI 08-45 |
Epidemiologic analysis of liver cancer in California |
Liver |
Screening/Diagnostic/ED |
Ou |
|
N/A |
|
UCI 08-46 |
Development of pancreatic cancer biomarkers: sourcing serum for cases and controls |
Pancreas |
Screening/Diagnostic/ED |
Anton-Culver |
|
N/A |
|
UCI 08-53 |
Epidemiology of Non-Small Cell Lung Cancer in the United States |
Lung |
Screening/Diagnostic/ED |
Zell |
|
N/A |
|
UCI 95-29 |
Measurement of Breast Optical Properties |
Breast - Female |
Screening/Diagnostic/ED |
Tromberg |
N/A |
Open |
|
UCI 98-20 |
Investigation Into the Molecular Events Involved in the Development of Cancer |
Multiple |
Correlative |
Holcombe |
N/A |
Open |
|
UCI 98-34 |
Bowman Birk Inhibitor Concentrate and Oral Leukoplakia: Phase IIb Trial (BBIC) |
Lip, Oral Cavity and Pharynx |
Prevention |
Meyskens |
II |
Open |
|
ZOO Z6041 |
A Phase II Trial of Neoadjuvant Chemoradiation and Local Excision for uT2uN0 Rectal Cancer |
Rectum |
Therapeutic |
Stamos |
II |
Open |
