Research Programs
CARCINOGENESIS PROGRAM
Co-leaders:
J.L. Redpath, Ph.D.
Professor and Vice Chair of Academic Affairs
Radiation Oncology
B148 Medical Sciences 1
Zot 2695
jlredpat@uci.edu
949.824.7395
Research Interests - Radiation-induced killing and neoplastic transformation of human cells. Influence of oncogenes, tumor suppressor genes, cytokines and chemotherapeutic agents.
Hans Ulrich Bernard, Ph.D.
Professor in Residence
Molecular Biology & Biochemistry
114 Sprague Hall – 150 Sprague Hall
Zot 3900
hbernard@uci.edu
949.824.5162 ext. 2435
Research Interests - Papillomaviruses and cervical cancer.
DEVELOPMENTAL BIOLOGY PROGRAM
Co-Leaders:
Bruce Blumberg, Ph.D.
Associate Professor, Developmental & Cell Biology
4103 Natural Sciences II
Zot 2305
blumberg@uci.edu
949.824.8573, 6873
Research Interests - Molecular embryology, molecular biology, developmental biology, functional genomics, endocrinology, pharmacology and high-throughput screening, nuclear hormone receptors and their role in embryonic development, adult physiology and cancer.
J. Lawrence Marsh, Ph.D.
Director, Developmental Biology Center
Professor, Developmental & Cell Biology
Room 4444 McGaugh Hall
University of California Irvine
Irvine, CA 92697-2300
jlmarsh@uci.edu
949.824-6677, 3266
http://dbc.bio.uci.edu/
http://devcell.bio.uci.edu/faculty/
Research Interests - Mechanisms of late onset Neurodegeneration - Oncogene signaling pathways in normal and abnormal growth.
POPULATION SCIENCES PROGRAM
Co-leaders:
Hoda Anton-Culver, Ph.D.
Professor and Chair, Department of Epidemiology
and
Director
GERI, Genetic Epidemiology Research Institute
Epidemiology, Genetic Epidemiology Research Institute
224 Irvine Hall – 100 Theory, Suite 100
Zot 7550
hantoncu@uci.edu
Research Interests - Cancer epidemiology, genetic epidemiology, statistical genetics, molecular genetics and medical informatics.
Susan Neuhausen, Ph.D.
Professor and Associate Director
Epidemiology, Genetic Epidemiology Research Institute
224 Irvine Hall – 218 Sprague Hall
Zot 7550
sneuhaus@uci.edu
949.824.5769
Research Interests - Genetic epidemiology, genetic susceptibility, genetic predisposition, breast cancer, celiac disease, prostate cancer and cancer genetics.
Theme Leaders:
Genetic Epidemiology:
Susan Neuhausen, Ph.D.
Professor and Associate Director
Epidemiology, Genetic Epidemiology Research Institute
224 Irvine Hall – 218 Sprague Hall
Zot 7550
sneuhaus@uci.edu
949.824.5769
Research Interests - Genetic epidemiology, genetic susceptibility, genetic predisposition, breast cancer, celiac disease, prostate cancer and cancer genetics.
Prevention:
Steve Lipkin, M.D., Ph.D.
Assistant Professor of Biological Chemistry
School of Medicine
250 Sprague Hall – 839 Medical Sciences Court
Zot 4038
slipkin@uci.edu
949.824.9219
Research Interest - DNA mismatch repair, chemoprevention trials of colorectal and pancreatic cancers as well as genetic epidemiology of colon cancer.
Cancer Control:
Lari Wenzel, Ph.D.
Associate Professor
Department of Medicine
UC Irvine Center for Health Policy Research
111 Academy, Suite 220
Zot 5800
lwenzel@uci.edu
949.824.3926
Research Interests - Evaluation of behaviors in cancer patients and survivors.
GROWTH FACTORS AND SIGNALING PROGRAM
Co-Leaders:
Marian Waterman, Ph.D.
Associate Professor and Vice Chair
Microbiology & Molecular Genetics Department
B251 Med Sci 1
Zot 4025
mlwaterm@uci.edu
949.824.2885
Research Interests - Wnt signaling, cancer, gene expression, immunology, nuclear trafficking, LEF and TCF transcription factors.
Christopher Hughes, Ph.D.
Professor
Molecular Biology & Biochemistry
3219 McGaugh Hall – Lab 3113 McGaugh Hall
Zot 3900
cchughes@uci.edu
949.824.8771, ext. 8143
Research Interests - Blood vessel development, angiogenesis in cancer and lymphocytes.
ONCO-IMAGING AND SPECTROSCOPY (OIS) PROGRAM
Co-Leaders:
Bruce Tromberg, Ph.D.
Professor and Director
Beckman Laser Institute
1002 Health Sciences Road E
Zot 1475
bjtrombe@uci.edu
949.824.8705
Research Interests - Lasers, near infrared spectroscopy, non-invasive diagnostics, photomedicine, biomedical optics and photodynamic therapy, translational cancer research
Orhan Nalcioglu, Ph.D.
Professor and Director
Radiological Sciences
164 Irvine Hall – SOM Tu & Yuen Center for Functional Onco-Imaging
Zot 5020
o.nalcioglu@uci.edu
949.824.6001
Research Interests - Nuclear magnetic resonance imaging and spectroscopy, digital radiography, computed tomography, medical imaging and functional onco-imaging.
STRUCTURAL MOLECULAR BIOLOGY PROGRAM
Co-Leaders:
Alex McPherson, Ph.D.
Professor
Molecular Biology & Biochemistry
School of Biological Sciences
560A Steinhaus Hall
Zot 3900
amcphers@uci.edu
949.824.1931
Research Interests - Research on macromolecular crystal growth, x-ray and diffraction analysis of protein, nucleic acid, virus crystals and atomic force microscopy studies of biological structures, cancer related retroviruses.
Patrick Farmer, Ph.D.
Professor
Chemistry
4142 Natural Science One
Zot 2025
pfarmer@uci.edu
949.824.6079
Research Interests - Inorganic and bioinorganic chemistry, the biochemistry of melanin and its dysregulation in melanoma, development of metal-based drugs and fluoroprobes of oxidative stress.
http://www.faculty.uci.edu/profile.cfm?faculty_id=2093
TRANSLATIONAL ONCOLOGY PROGRAM
Co-Leaders:
John Fruehauf, M.D.
Associate Clinical Professor
Hematology/Oncology, Department of Medicine
Bldg. 55, Room 324
Zot 4061
jfruehau@uci.edu
714.456.5153
Research Interests - Mechanisms of drug action and resistance with the goal of improving therapeutic outcomes for cancer patients.
Michael Lilly, M.D.
Professor of Clinical Medicine and
Vice Chief of Hematology/Oncology
Department of Medicine, Hematology/Oncology
Bldg. 56, Room 248
Zot 4061
mlilly@uci.edu
714.456.5153
Research Interests– Molecular target to modulate cellular resistance to therapy in prostate cancer.